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SB 674042, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
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483313-22-0
C24H21FN4O2S
448.516
HYBZWVLPALMACV-KRWDZBQOSA-N
5-2-fluorophenyl-2-methyl-1,3-thiazol-4-yl-2s-2-5-phenyl-1,3,4-oxadiazol-2-yl methyl pyrrolidin-1-yl methanone,2-2s-1-5-2-fluorophenyl-2-methyl-1,3-thiazole-4-carbonyl pyrrolidin-2-yl methyl-5-phenyl-1,3,4-oxadiazole,5-2-fluorophenyl-2-methyl-1,3-thiazol-4-yl 2s-2-5-phenyl-1,3,4-oxadiazol-2-yl methyl pyrrolidin-1-yl methanone,5-2-fluorophenyl-2-methyl-4-thiazolyl 2 s-2-5-phenyl-1,3,4-oxadiazol-2-yl methyl-1-pyrrolidinyl methanone,4ot
10204153
[5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl]methanone
CC1=NC(=C(S1)C2=CC=CC=C2F)C(=O)N3CCCC3CC4=NN=C(O4)C5=CC=CC=C5
This item is not returnable. View return policy
483313-22-0
C24H21FN4O2S
448.516
HYBZWVLPALMACV-KRWDZBQOSA-N
5-2-fluorophenyl-2-methyl-1,3-thiazol-4-yl-2s-2-5-phenyl-1,3,4-oxadiazol-2-yl methyl pyrrolidin-1-yl methanone,2-2s-1-5-2-fluorophenyl-2-methyl-1,3-thiazole-4-carbonyl pyrrolidin-2-yl methyl-5-phenyl-1,3,4-oxadiazole,5-2-fluorophenyl-2-methyl-1,3-thiazol-4-yl 2s-2-5-phenyl-1,3,4-oxadiazol-2-yl methyl pyrrolidin-1-yl methanone,5-2-fluorophenyl-2-methyl-4-thiazolyl 2 s-2-5-phenyl-1,3,4-oxadiazol-2-yl methyl-1-pyrrolidinyl methanone,4ot
10204153
[5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl]methanone
CC1=NC(=C(S1)C2=CC=CC=C2F)C(=O)N3CCCC3CC4=NN=C(O4)C5=CC=CC=C5

Potent and selective non-peptide OX1 antagonist

Potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM). Exhibits 100-fold selectivity for OX1 over OX2 receptors. Has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 receptor.

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Quantity 50mg
Formula Weight 448.51
Chemical Name or Material SB 674042

Recommended Storage : Store at +4°C