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Tocris Bioscience™ SB 706504
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Catalog No. 504050
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50-405-0 50 mg
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Catalog No. 50-405-0 Supplier Tocris Bioscience™ Supplier No. 5040/50
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Description

p38 MAPK inhibitor

SB 706504 is a p38 MAPK inhibitor. Inhibits LPS-induced transcription of a range of chemokines and cytokines in chronic obstructive pulmonary disease (COPD) monocyte derived macrophages (MDMs). Also inhibits LPS-induced protein expression of IL-6, IL-10, TNFα and γ-inducible protein 10 in COPD MDMs. Effects on suppression of LPS-induced gene and protein expression are enhanced in combination with dexamethasone (Cat. No. 1126).

Specifications

Chemical Name or Material N-Cyano-N′-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine
CAS 911110-38-8
Quantity 50 mg
Target p38 Inhibitors
Molecular Formula C24H19F3N8O
Formula Weight 492.46
Purity >98%
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