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Tocris Bioscience™ SC 144 hydrochloride 
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
Manufacturer: Tocris Bioscience™ 4963/10
Description
Inhibitor of gp130 (IC50 = 0.72 μM); blocks cytokine-triggered gp130 signaling. Induces gp130 phosphorylation and down regulates gp130 glycosylation; also abrogates STAT3 phosphorylation, nuclear translocation and inhibits the expression of downstream target genes. Delays tumor growth in a mouse xenograft model of human ovarian cancer. Orally active.This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.
Specifications
| SC 144 hydrochloride | |
| >99 | |
| 10mg |
| SC 144 hydrochloride | |
| 358.76 |
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