Invitrogen™ SCAMP2 Monoclonal Antibody (OTI1H10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526296

Catalog No. PIMA526296

Description

SCAMP2 Monoclonal Antibody for Western Blot, IHC (P)

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Specifications

• Antigen: SCAMP2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O15127
• Gene Symbols: Scamp2
• Immunogen: Full length human recombinant protein of SCAMP2 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1H10
• Conjugate: Unconjugated
• Gene: Scamp2
• Gene Alias: AI875466; I79_023583; Sc2; scamp 2; SCAMP2; Secretory carrier membrane protein 2; secretory carrier-associated membrane protein 2; testis secretory sperm-binding protein Li 219p
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10066
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid