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Invitrogen™ SCAMP2 Monoclonal Antibody (OTI3C2)
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Catalog No. PIMA526297
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100 μL
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PIMA526297 100 μL
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Catalog No. PIMA526297 Supplier Invitrogen™ Supplier No. MA526297
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Description

Mouse Monoclonal Antibody

SCAMP2 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCAMP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone OTI3C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Scamp2
Gene Accession No. O15127
Gene Alias AI875466; I79_023583; Sc2; scamp 2; SCAMP2; Secretory carrier membrane protein 2; secretory carrier-associated membrane protein 2; testis secretory sperm-binding protein Li 219p
Gene Symbols Scamp2
Host Species Mouse
Immunogen Full length human recombinant protein of SCAMP2 produced in HEK293T cell.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10066
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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