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SCAMP2 Mouse anti-Human, Clone: OTI3C2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF506991

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.Specifications
SCAMP2 | |
Monoclonal | |
Unconjugated | |
SCAMP2 | |
secretory carrier membrane protein 2 | |
Mouse | |
Affinity Chromatography | |
RUO | |
10066 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI3C2 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
O15127 | |
SCAMP2 | |
Full length human recombit protein of human SCAMP2 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a |
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