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SCAMP2 Mouse anti-Human, Clone: OTI3C2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF506991

Encompass_Preferred

Catalog No. 50-166-4576


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
Specifications

Specifications

SCAMP2
Monoclonal
Unconjugated
SCAMP2
secretory carrier membrane protein 2
Mouse
Affinity Chromatography
RUO
10066
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3C2
PBS with 8% trehalose and no preservative; pH 7.3
O15127
SCAMP2
Full length human recombit protein of human SCAMP2 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG2a
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