Invitrogen™ SCAMP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114149

Catalog No. PIPA5114149

Description

Immunogen sequence: VFSFIALSMV HKFYRGSGGS FSKAQEEWTT GAWKNPHVQQ AAQNAAMGAA For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Specifications

• Antigen: SCAMP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCAMP5
• Gene Alias: hSCAMP5; Sc5; scamp5; scamp5a; Secretory carrier membrane protein 5; secretory carrier membrane protein 5a; secretory carrier membrane protein 5-like; secretory carrier-associated membrane protein 5; wu:fc30b07; zgc:77438
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56807
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9JKD3
• Gene Symbols: SCAMP5
• Immunogen: Immunogen sequence: VFSFIALSMV HKFYRGSGGS FSKAQEEWTT GAWKNPHVQQ AAQNAAMGAA (aa 163-212).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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