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SCAP2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983069
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50-198-3069 100 μL
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Catalog No. 50-198-3069 Supplier Bioss Supplier No. BS13673R
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Description

Rabbit Polyclonal Antibody

Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.

Specifications

Antigen SCAP2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SKAP2
Gene Accession No. O75563
Gene Alias 2610021A10Rik; AA960083; BB137539; Fyn-associated phosphoprotein SKAP55 homologue; MGC10411; MGC33304; mSKAP55R; Prap; Pyk2/RAFTK-associated protein; Ra70; Retinoic acid-induced protein 70; Saps; Scap2; Scap55r; Skap2; SKAP55 homolog; SKAP55 homologue; SKAP-55HOM; SKAP55-HOM; SKAP55R; SKAP-HOM; src family associated phosphoprotein 2; Src family-associated phosphoprotein 2; src kinase associated phosphoprotein 2; Src kinase-associated phosphoprotein 2; Src kinase-associated phosphoprotein 55-related protein; src kinase-associated phosphoprotein of 55-related protein; Src-associated adapter protein with PH and SH3 domains; Src-associated adaptor protein
Gene Symbols SKAP2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SCAP2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8935
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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