Invitrogen™ SCARA5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520766

Catalog No. PIPA520766

Description

A suggested positive control is human spleen tissue lysate. PA5-20766 can be used with blocking peptide PEP-0880.

Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains that collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery. At least four isoforms of SCARB1 are known to exist.

Specifications

• Antigen: SCARA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCARA5
• Gene Alias: 4932433F15Rik; 4933425F03Rik; AV278087; NET33; SCARA5; Scavenger receptor class A member 5; scavenger receptor class A, member 5 (putative); scavenger receptor hlg; Tesr; testis expressed scavenger receptor; UNQ2938/PRO28700
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286133
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6ZMJ2
• Gene Symbols: SCARA5
• Immunogen: A 17 amino acid peptide near the carboxy terminus of human SCARA5.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG