Invitrogen™ SCCPDH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531943

Catalog No. PIPA531943

Description

Recommended positive controls: U87-MG. Predicted reactivity: Human (99%), Mouse (85%), Rat (87%), Pig (84%), Chimpanzee (98%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C. elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Specifications

• Antigen: SCCPDH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCCPDH
• Gene Alias: AW214504; C330023F11Rik; CGI 49; CGI49; CGI-49; hypothetical protein LOC507289; NET11; probable saccharopine dehydrogenase; RGD1311440; RP11-439E19.2; saccharopine dehydrogenase (putative); saccharopine dehydrogenase-like oxidoreductase; Sccpdh; SCPDH
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51097
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8NBX0
• Gene Symbols: SCCPDH
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 37 and 230 of Human SCCPDH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG