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Invitrogen™ SCD Polyclonal Antibody
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Catalog No. PIPA522996
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100 μL
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PIPA522996 100 μL
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Catalog No. PIPA522996 Supplier Invitrogen™ Supplier No. PA522996
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Description

Rabbit Polyclonal Antibody

Suggested positive control: whole normal human liver lysate.

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5., have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCD
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.1% sodium azide
Gene Scd
Gene Accession No. O00767
Gene Alias AA589638; ab; acyl-CoA desaturase; Acyl-CoA desaturase 1; acyl-CoA desaturase 2; AI265570; asebia; delta(9)-desaturase; Delta(9)-desaturase 1; delta(9)-desaturase 2; Delta-9 desaturase; delta-9 desaturase 1; Delta-9 desaturase 2; delta-9-desaturase; FADS5; fatty acid desaturase; Fatty acid desaturase 1; fatty acid desaturase 2; HGNC:10571; hSCD1; MSTP008; OTTHUMP00000020280; predicted protein of HQ0998; PRO0998; PRO1933; Scd; Scd1; Scd-1; Scd2; SCDOS; stearoyl-CoA desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase 1; Stearoyl-CoA desaturase 2; stearoyl-CoA desaturase opposite strand; stearoyl-Coenzyme A desaturase 1; stearoyl-Coenzyme A desaturase 2; stearyl-CoA desaturase
Gene Symbols Scd
Host Species Rabbit
Immunogen Synthetic peptide made to an internal portion of human SCD (within residues 50-100).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6319
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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