SCD/SCD1/Stearoyl-CoA Desaturase Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-9911	Bethyl Laboratories, Inc A305244AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999); Wang et al., 2005).

Specifications

• Antigen: SCD/SCD1/Stearoyl-CoA Desaturase
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: OTTHUMP00000020280; acyl-CoA desaturase; delta(9)-desaturase; delta-9-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase opposite strand
• Gene Symbols: SCD
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O00767
• Gene ID (Entrez): 6319
• Immunogen: Between 1 and 50
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: SCD