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SCD/SCD1/Stearoyl-CoA Desaturase Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501569951
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50-156-9951 100 μL
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Catalog No. 50-156-9951 Supplier Bethyl Laboratories, Inc Supplier No. A305259A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999); Wang et al., 2005).

Specifications

Antigen SCD/SCD1/Stearoyl-CoA Desaturase
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene SCD
Gene Accession No. O00767
Gene Alias OTTHUMP00000020280; acyl-CoA desaturase; delta(9)-desaturase; delta-9-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase opposite strand
Gene Symbols SCD
Host Species Rabbit
Immunogen Between 25 and 75
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6319
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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