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Invitrogen™ SCG5 Polyclonal Antibody
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Catalog No. PIPA570632
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100 μL
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Catalog No. Quantity
PIPA570632 100 μL
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Catalog No. PIPA570632 Supplier Invitrogen™ Supplier No. PA570632
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%.

Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCG5
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Scg5
Gene Accession No. P05408
Gene Alias 7B2; AI325031; C-terminal peptide; hypothetical protein MGC73132; LOC508224 protein; Neuroendocrine protein 7B2; neuronal endocrine protein; N-terminal peptide; P SGNE1; P7B2; pituitary polypeptide; prohormone convertase chaperone; SCG5; Secretogranin V; secretogranin V (7B2 protein); secretogranin-5; Secretory granule endocrine protein I; secretory granule neuroendocrine protein 1; secretory granule neuroendocrine protein 1, 7B2 protein; Secretory granule neuroendocrine, protein 1 (7B2 protein); secretory granule, neuroendocrine protein 1; secretory granule, neuroendocrine protein 1 (7B2 protein); SGNE1; Sgne-1; SgV; zgc:73132
Gene Symbols Scg5
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human SCG5 (aa 70-119).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6447
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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