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Invitrogen™ SCG5 Polyclonal Antibody
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Catalog No. PIPA5111721
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Quantity:
100 μL
Catalog No. Quantity
PIPA5111721 100 μL
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Catalog No. PIPA5111721

Supplier: Invitrogen™ PA5111721

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AYSPRTPDRV SEADIQRLLH GVMEQLGIAR PRVEYPAHQA MNLVGPQSIE GGAHE Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 98%.

Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCG5
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Scg5
Gene Accession No. P05408
Gene Alias 7B2; AI325031; C-terminal peptide; hypothetical protein MGC73132; LOC508224 protein; Neuroendocrine protein 7B2; neuronal endocrine protein; N-terminal peptide; P SGNE1; P7B2; pituitary polypeptide; prohormone convertase chaperone; SCG5; Secretogranin V; secretogranin V (7B2 protein); secretogranin-5; Secretory granule endocrine protein I; secretory granule neuroendocrine protein 1; secretory granule neuroendocrine protein 1, 7B2 protein; Secretory granule neuroendocrine, protein 1 (7B2 protein); secretory granule, neuroendocrine protein 1; secretory granule, neuroendocrine protein 1 (7B2 protein); SGNE1; Sgne-1; SgV; zgc:73132
Gene Symbols Scg5
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human SCG5. Recombinant protein control fragment (Product #RP-108636).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6447
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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