Invitrogen™ SCIN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112705

Catalog No. PIPA5112705

Description

SCIN Polyclonal Antibody for Western Blot, ICC/IF, ELISA

The SCIN gene, also known as scinderin, encodes for a calcium-dependent actin filament-severing protein that is involved in the regulation of the cytoskeleton. It plays a significant role in actin filament dynamics, influencing cellular processes such as cell shape, motility, secretion, and division. SCIN has been identified as a novel oncogene, with its abnormal expression strongly correlated to various cancers, including glioma and uterine corpus endometrial carcinoma. Specific mutations like S673F and S381Y in SCIN are linked with poor prognosis and are potential targets for cancer diagnosis, prognosis, and treatment strategies.

Specifications

• Antigen: SCIN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCIN
• Gene Alias: Adseverin; AW545522; Gelsolin-like protein; KIAA1905; SCIN; Scind; Scinderin
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 20259, 85477
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 7 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q60604, Q9Y6U3
• Gene Symbols: SCIN
• Immunogen: Recombinant Human Adseverin protein (556-703AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG