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Invitrogen™ SCLY Monoclonal Antibody (3B2)
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Catalog No. PIMA521953
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100 μg
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Catalog No. Quantity
PIMA521953 100 μg
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Catalog No. PIMA521953 Supplier Invitrogen™ Supplier No. MA521953
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Description

Mouse Monoclonal Antibody

Peptide Sequence: NSQFPGTQRL PNTCNFSIRG PRLQGHVVLA QCRVLMASVG AACHSDHGDQ PSPVLLSYGV PFDVARNALR LSVGRSTTRA EVDLVVQDLK QAVAQLEDQ.

The SCLY gene encodes selenocysteine lyase, an enzyme involved in selenium metabolism, which plays a critical role in the recycling of selenocysteine from selenoproteins. SCLY catalyzes the conversion of selenocysteine into alanine, releasing selenium for reuse in the biosynthesis of new selenoproteins. It is chiefly active in the liver and kidneys, contributing to maintaining selenium homeostasis, which is vital for numerous biological functions due to selenium's role in antioxidant defense and thyroid hormone metabolism. Alterations in SCLY function or expression can affect selenium levels in the body and are associated with disorders related to oxidative stress and metabolic imbalances. Given the importance of selenium in cellular protection and immune function, SCLY is also of interest in studies focusing on dietary supplementation and disease prevention strategies, particularly in conditions like cancer and cardiovascular diseases where oxidative damage is prevalent.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCLY
Applications ELISA, Immunoprecipitation
Classification Monoclonal
Clone 3B2
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Scly
Gene Accession No. Q96I15
Gene Alias 9830169H08; A930015N15Rik; hSCL; mSCL; SCL; SCLY; Scly1; Scly2; Selenocysteine lyase; selenocysteine lyase; Selenocysteine reductase; selenocysteine reductase
Gene Symbols Scly
Host Species Mouse
Immunogen SCLY (NP_057594, 346 a.a. ~ 444 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51540
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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