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Invitrogen™ SCLY Polyclonal Antibody
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Catalog No. PIPA563172
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100 μL
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PIPA563172 100 μL
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Catalog No. PIPA563172 Supplier Invitrogen™ Supplier No. PA563172
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LYPMLFGGGQ ERNFRPGTEN TPMIAGLGKA AELVTQNCEA YEAHMRDVRD YLEERLEAEF GQKRIHLNS Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%.

The SCLY gene encodes selenocysteine lyase, an enzyme involved in selenium metabolism, which plays a critical role in the recycling of selenocysteine from selenoproteins. SCLY catalyzes the conversion of selenocysteine into alanine, releasing selenium for reuse in the biosynthesis of new selenoproteins. It is chiefly active in the liver and kidneys, contributing to maintaining selenium homeostasis, which is vital for numerous biological functions due to selenium's role in antioxidant defense and thyroid hormone metabolism. Alterations in SCLY function or expression can affect selenium levels in the body and are associated with disorders related to oxidative stress and metabolic imbalances. Given the importance of selenium in cellular protection and immune function, SCLY is also of interest in studies focusing on dietary supplementation and disease prevention strategies, particularly in conditions like cancer and cardiovascular diseases where oxidative damage is prevalent.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCLY
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Scly
Gene Accession No. Q96I15
Gene Alias 9830169H08; A930015N15Rik; hSCL; mSCL; SCL; SCLY; Scly1; Scly2; Selenocysteine lyase; selenocysteine lyase; Selenocysteine reductase; selenocysteine reductase
Gene Symbols Scly
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SCLY. Recombinant protein control fragment (Product #RP-103918).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51540
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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