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Invitrogen™ SCN1B Polyclonal Antibody
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Catalog No. PIPA5104157
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100 μL
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PIPA5104157 100 μL
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Catalog No. PIPA5104157 Supplier Invitrogen™ Supplier No. PA5104157
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SCN1B.

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCN1B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Scn1b
Gene Accession No. P97952, Q00954, Q07699
Gene Alias ATFB13; BRGDA5; GEFSP1; Scn1b; sodium channel beta 1-subunit; sodium channel beta-1 subunit; sodium channel subunit beta-1; sodium channel voltage-gated type 1 beta polypeptide; sodium channel voltage-gated type I beta polypeptide; sodium channel, voltage gated, type I beta subunit; sodium channel, voltage-gated, type 1, beta polypeptide; sodium channel, voltage-gated, type I, beta; sodium channel, voltage-gated, type I, beta polypeptide; sodium channel, voltage-gated, type I, beta subunit; sodium voltage-gated channel beta subunit 1
Gene Symbols Scn1b
Host Species Rabbit
Immunogen A synthesized peptide derived from human SCN1B(Accession Q07699), corresponding to amino acid residues K184-E218.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20266, 29686, 6324
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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