SCN2B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 136121AP150UL

Catalog No. 50-172-8873

Description

Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IIbeta (sodium channel, voltage-gated, typeII, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type IIbeta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.

Specifications

• Antigen: SCN2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCN2B
• Gene Alias: SCN2B, Sodium channel subunit beta 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25349, 6327, 72821
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60939, P54900, Q56A07
• Gene Symbols: Scn2b
• Immunogen: SCN2B Fusion Protein Ag4515
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG