Invitrogen™ SCN3B Monoclonal Antibody (N396/29)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527618

Catalog No. PIMA527618

Description

A 1:100 dilution of MA5-27618 was sufficient for detection of NavBeta3 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 40kDa. Does not cross-reat with NavBeta1, Navbeta2, or Navbeta4. This antibody was formerly sold as clone S396-29.

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: SCN3B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
• Gene Accession No.: Q8BHK2, Q9JK00, Q9NY72
• Gene Symbols: Scn3b
• Immunogen: Fusion protein amino acids 1-215 (full-length) of rat NavBeta3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot, Immunocytochemistry
• Clone: N396/29
• Conjugate: Unconjugated
• Gene: Scn3b
• Gene Alias: 1110001K16Rik; 4833414B02Rik; ATFB16; brain and heart sodium channel beta 3 subunit; BRGDA7; HSA243396; KIAA1158; LOC540925 protein; Scn3b; Scnb3; sodium channel beta 3 subunit; sodium channel subunit beta-3; sodium channel, voltage gated, type III beta subunit; sodium channel, voltage-gated, type III, beta; sodium channel, voltage-gated, type III, beta subunit; sodium voltage-gated channel beta subunit 3; voltage-gated sodium channel beta-3 subunit
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 235281, 245956, 55800
• Content And Storage: -20°C
• Form: Liquid