SCNN1D Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0712	100 μL

Catalog No. 50-198-0712 Supplier Bioss Supplier No. BS10141R

Description

Rabbit Polyclonal Antibody

SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.

Specifications

• Antigen: SCNN1D
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: SCNN1D
• Gene Accession No.: P51172
• Gene Alias: Amiloride-sensitive sodium channel subunit delta; Delta-ENaC; Delta-NaCH; DNACH; ENaCd; ENaCdelta; Epithelial Na(+) channel subunit delta; MGC149710; Nonvoltage-gated sodium channel 1 subunit delta; SCNED; SCNN1D; sodium channel epithelial 1 delta subunit; sodium channel, non voltage gated 1 delta subunit; sodium channel, nonvoltage-gated 1, delta; sodium channel, non-voltage-gated 1, delta subunit; sodium channel, voltage-gated, type I, delta polypeptide
• Gene Symbols: SCNN1D
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human SCNN1D.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6339
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG