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SCO2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501733328 Shop All Proteintech Group Inc Products
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50-173-3328 150 μL
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Catalog No. 50-173-3328 Supplier Proteintech Group Inc Supplier No. 212231AP150UL
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Description

Rabbit Polyclonal Antibody

Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.

Specifications

Antigen SCO2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SCO2
Gene Accession No. O43819, Q8VCL2
Gene Alias SCO1L, SCO2
Gene Symbols SCO2
Host Species Rabbit
Immunogen SCO2 Fusion Protein Ag15663
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100126824, 9997
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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