Invitrogen™ SCP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555519

Catalog No. PIPA555519

Description

Immunogen sequence: GKKALADAQI PYSAVDQACV GYVFGDSTCG QRAIYHSLGM TGIPIINVNN NCATGSTALF MARQLIQGGV AECVLALGFE KMSKGSLGIK FSDRTIPTDK H Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Specifications

• Antigen: SCP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCP2
• Gene Alias: AA409774; AA409893; C76618; C79031; NLTP; nonspecific lipid transfer protein; Non-specific lipid-transfer protein; NSLIPTR; ns-LTP; NSL-TP; propanoyl-CoA C-acyltransferase; SCP2; SCP-2; SCP-CHI; SCPX; SCP-X; Sterol carrier protein 2; sterol carrier protein 2, liver; sterol carrier protein X
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20280, 25541, 6342
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P11915, P22307, P32020
• Gene Symbols: SCP2
• Immunogen: Recombinant protein corresponding to Human SCP2. Recombinant protein control fragment (Product #RP-94062).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG