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Invitrogen™ SCUBE1 Polyclonal Antibody
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Catalog No. PIPA520990
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100 μg
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Catalog No. Quantity
PIPA520990 100 μg
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Catalog No. PIPA520990 Supplier Invitrogen™ Supplier No. PA520990
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Daudi cell lysate. PA5-20990 can be used with blocking peptide PEP-1104.

SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCUBE1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SCUBE1
Gene Accession No. Q8IWY4
Gene Alias 7330410C13Rik; A630023E24Rik; im:7427863; SCUBE1; signal peptide; Signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB and EGF-like domain-containing protein 1; LOW QUALITY PROTEIN: signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB domain and EGF like domain containing 1; signal peptide, CUB domain, EGF-like 1; signal peptide-CUB domain-EGF-related 1
Gene Symbols SCUBE1
Host Species Rabbit
Immunogen A 14 amino acid peptide near the center of human SCUBE1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80274
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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