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Invitrogen™ SCUBE2 Polyclonal Antibody
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Catalog No. PIPA556278
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100 μL
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PIPA556278 100 μL
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Catalog No. PIPA556278 Supplier Invitrogen™ Supplier No. PA556278
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SGIHLSSDVT TIRTSVTFKL NEGKCSLKNA ELFPEGLRPA LPEKHSSVKE SFRYVNLTCS SGKQVPGAPG RPSTPKEMFI TVEFELETNQ KEVTASCDLS CIVKRTEKRL RKAIRTLRKA VHREQFHLQL SGMNLDVAK Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 83%.

SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCUBE2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SCUBE2
Gene Accession No. Q9NQ36
Gene Alias CEGB1; CEGF1; CEGP1; Protein CEGP1; RGD1563998; Scube/You; SCUBE2; Scube2-ps1; signal peptide; Signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain and EGF like domain containing 2; signal peptide, CUB domain, EGF-like 2; signal peptide, CUB domain, EGF-like 2, pseudogene 1
Gene Symbols SCUBE2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SCUBE2. Recombinant protein control fragment (Product #RP-88796).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57758
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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