Invitrogen™ SDCCAG8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111696

Catalog No. PIPA5111696

Description

Immunogen sequence: LIQCDQLRKE LERQAERLEK ELASQQEKRA IEKDMMKKEI TKEREYMGSK MLILSQNIAQ LEAQVEKVTK EKISAINQLE EIQSQLASRE MDVTKV.

SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Specifications

• Antigen: SDCCAG8
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86SQ7
• Gene Symbols: SDCCAG8
• Immunogen: Recombinant Protein corresonding to Human SDCCAG8. Recombinant protein control fragment (Product #RP-107882).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry
• Conjugate: Unconjugated
• Gene: SDCCAG8
• Gene Alias: 2700048G21Rik; 5730470G24Rik; Antigen NY-CO-8; BBS16; CCCAP; CCCAP SLSN7; centrosomal colon cancer autoantigen protein; hCCCAP; HSPC085; mCCCAP; NPHP10; NY-CO-8; SDCCAG8; Serologically defined colon cancer antigen 8; serologically defined colon cancer antigen 8 homolog; SHH signaling and ciliogenesis regulator sdccag8; si:dkey-60b15.1; slinky; SLSN7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10806
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid