Invitrogen™ SDHA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596179

Catalog No. PIPA596179

Description

Immunogen sequence: ETAMIFAGVD VTKEPIPVLP TVHYNMGGIP TNYKGQVLRH VNGQDQIVPG LYACGEAACA SVHGANRLGA NSLLDLVVFG RACALSIEES CRPGDKVPPI KPNAGEESVM NLDKLRFADG SIRTSELRLS MQKSMQNHAA VFRVGSVLQE GCGKISKLYG DLKHLKTFDR GMVWNTDLVE TLELQNLMLC ALQTIYGAEA RKESRGAHAR EDYKVRIDEY DYSKPIQGQQ KKPFEEHWRK HTLSYVDVGT GKVTLEYRPV IDKTLNEADC ATVPPAIRSY; Positive Samples: HepG2, U-251MG, PC-3, MCF7, Mouse liver, Mouse stomach, NCI-H125; Cellular Location: Matrix side, Mitochondrion inner membrane, Peripheral membrane protein.

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.

Specifications

• Antigen: SDHA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SDHA
• Gene Alias: 1500032O14Rik; 2310034D06Rik; 4921513A11; C81073; CMD1GG; Flavoprotein subunit of complex II; FP; im:7141001; mitochondrial succinate dehydrogenase complex subunit A; PGL5; SDH1; SDH2; SDHA; SDHA protein; SDHF; SDHFP1; si:dkeyp-84f11.2; succinate dehydrogenase [ubiquinone] flavoprotein subunit; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; succinate dehydrogenase complex flavoprotein subunit A; succinate dehydrogenase complex subunit A; succinate dehydrogenase complex subunit A flavoprotein; succinate dehydrogenase complex subunit A, flavoprotein (Fp); succinate dehydrogenase complex, subunit A, flavoprotein (Fp); succinate dehydrogenase flavoprotein subunit; succinate dehydrogenase flavoprotein subunit A; zgc:56051
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 157074, 6389, 66945
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.54 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P31040, Q8K2B3, Q920L2
• Gene Symbols: SDHA
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 385-664 of human SDHA (NP_0041592).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG