Invitrogen™ SDHB Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518407

Catalog No. PIPA518407

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Specifications

• Antigen: SDHB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sdhb
• Gene Alias: 0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 6390
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P21912
• Gene Symbols: Sdhb
• Immunogen: Synthetic peptide sequence (ATYKEKKASV) corresponding to the C-terminus amino acids of SDHB (aa 271-280).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov