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Invitrogen™ SDHB Polyclonal Antibody
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Catalog No. PIPA523079
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100 μL
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PIPA523079 100 μL
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Catalog No. PIPA523079 Supplier Invitrogen™ Supplier No. PA523079
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Description

Rabbit Polyclonal Antibody

The target sequence has 92% sequence homology with rat, bovine and porcine, 85% sequence homology with xenopus and 84% sequence homology with zebrafish.

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SDHB
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.05% sodium azide
Gene Sdhb
Gene Accession No. P21912, P21913, Q9CQA3
Gene Alias 0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06
Gene Symbols Sdhb
Host Species Rabbit
Immunogen A genomic peptide made to an N-terminal region of the human SDHB protein (within residues 1-150).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 298596, 6390, 67680
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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