SDHB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6454	Proteintech Group Inc 106201AP150UL	150 μL

Description

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Specifications

• Antigen: SDHB
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P21912, P21913, Q9CQA3
• Gene ID (Entrez): 298596, 6390, 67680
• Immunogen: SDHB Fusion Protein Ag0968
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SDHB

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: IP, PGL4, SDH, SDH1, SDHB, SDHIP
• Gene Symbols: SDHB
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody