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Invitrogen™ SDHB Recombinant Rabbit Monoclonal Antibody (HL2251)
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Catalog No. FEMA550457
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100 μL
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FEMA550457 100 μL
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Catalog No. FEMA550457 Supplier Invitrogen™ Supplier No. MA550457
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Rabbit Recombinant Monoclonal Antibody

SDHB Recombinant Monoclonal Antibody for Western Blot, IHC (P)

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SDHB
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone HL2251
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Sdhb
Gene Accession No. P21912
Gene Alias 0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06
Gene Symbols Sdhb
Host Species Rabbit
Immunogen Recombinant fragment of human SDHB.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6390
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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