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Invitrogen™ SDPR Polyclonal Antibody
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Catalog No. PIPA5115877
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100 μL
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PIPA5115877 100 μL
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Catalog No. PIPA5115877 Supplier Invitrogen™ Supplier No. PA5115877
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SDPR.

The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SDPR
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene CAVIN2
Gene Accession No. O95810, Q63918, Q66H98
Gene Alias caveolae associated protein 2; caveolae-associated protein 2; cavin 2; CAVIN2; cavin-2; EMBL:AAH81956.1}; phosphatidylserine binding protein; phosphatidylserine-binding protein; PS-p68; SDPR; sdpr {ECO:0000312; SDR; serum deprivation response; serum deprivation response protein; serum deprivation-response protein
Gene Symbols CAVIN2
Host Species Rabbit
Immunogen A synthesized peptide derived from human CAVIN2(Accession O95810), corresponding to amino acid residues E213-V263.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20324, 316384, 8436
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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