SDPR Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS19605R

Catalog No. 50-198-4351

Description

The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.

Specifications

• Antigen: SDPR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAVIN2
• Gene Alias: BOS_1929; caveolae associated protein 2; Caveolae-associated protein 2; cavin 2; CAVIN2; Cavin-2; EMBL:AAH81956.1}; phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS-p68; Sdpr; sdpr {ECO:0000312; Sdr; serum deprivation response; serum deprivation response protein; Serum deprivation-response protein
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8436
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: O95810
• Gene Symbols: CAVIN2
• Immunogen: KLH conjugated synthetic peptide derived from human SDPR.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG