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SDPR Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984351
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50-198-4351 100 μL
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Catalog No. 50-198-4351 Supplier Bioss Supplier No. BS19605R
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Description

Rabbit Polyclonal Antibody

The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.

Specifications

Antigen SDPR
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CAVIN2
Gene Accession No. O95810
Gene Alias BOS_1929; caveolae associated protein 2; Caveolae-associated protein 2; cavin 2; CAVIN2; Cavin-2; EMBL:AAH81956.1}; phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS-p68; Sdpr; sdpr {ECO:0000312; Sdr; serum deprivation response; serum deprivation response protein; Serum deprivation-response protein
Gene Symbols CAVIN2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SDPR.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8436
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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