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Tocris Bioscience™ SDZ NKT 343
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Catalog No. 239410
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23-941-0 10 mg
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Highly selective, human NK1 antagonist

Highly selective human tachykinin NK1 receptor antagonist (IC50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK2 and NK3 receptors. Potently antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo.

Specifications

CAS 180046-99-5
Quantity 10 mg
Product Type SDZ NKT 343
Purity >98%
Molecular Weight (g/mol) 579.657
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