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Invitrogen™ SEC14L1 Polyclonal Antibody
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Catalog No. PIPA554415
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100 μL
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PIPA554415 100 μL
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Catalog No. PIPA554415 Supplier Invitrogen™ Supplier No. PA554415
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Rabbit Polyclonal Antibody

Immunogen sequence: AMKQYTSNIK KGKEIIEYYL RQLEEEGITF VPRWSPPSIT PSSETSSSSS KKQAASMAVV IPEAALKEGL SGDALSSPSA PEPVVGTPDD Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 78%.

SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEC14L1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SEC14L1
Gene Accession No. Q92503
Gene Alias PRELID4A; SEC14 like lipid binding 1; SEC14L; SEC14L1; SEC14-like protein 1
Gene Symbols SEC14L1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SEC14L1. Recombinant protein control fragment (Product #RP-102544).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6397
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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