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Invitrogen™ SEC61A1 Polyclonal Antibody
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Catalog No. PIPA521773
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100 μL
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PIPA521773 100 μL
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Catalog No. PIPA521773 Supplier Invitrogen™ Supplier No. PA521773
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: K562 whole cell extract, K562 membrane fraction extract (un-boiled). Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Dog (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEC61A1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene SEC61A1
Gene Accession No. P61619
Gene Alias AA408394; AA410007; homologue to sec61; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; protein transport protein Sec61 subunit alpha isoform 1; protein transport protein Sec61 subunit alpha isoform 1; protein transport protein Sec61 subunit alpha; SEC61; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha subunit homolog; sec61 alpha-1; sec61 homolog; sec61 homologue; SEC61 translocon alpha 1 subunit; SEC61 translocon subunit alpha 1; SEC61, alpha subunit; SEC61A; SEC61A1; transport protein sec61 alpha subunit
Gene Symbols SEC61A1
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SEC61A1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29927
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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