Invitrogen™ SEC61B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585603

Catalog No. PIPA585603

Description

Keep as concentrated solution. Predicted reactivity: Dog (100%), Pig (100%). Positive Control: 293T, A431, HeLa, HepG2, mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.

Specifications

• Antigen: SEC61B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEC61B
• Gene Alias: 1190006C12Rik; AI326121; AW122942; protein translocation complex beta; protein translocation complex beta subunit; protein transport protein SEC61 beta subunit; protein transport protein Sec61 subunit beta; sec61 beta; Sec61 beta subunit; Sec61 complex, beta subunit; SEC61 translocon beta subunit; SEC61 translocon subunit beta; Sec61b
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10952, 66212
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.77 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P60468, Q9CQS8
• Gene Symbols: SEC61B
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SEC61B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov