Invitrogen™ SEC62 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535972

Catalog No. PIPA535972

Description

Recommended positive controls: 293T, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq].

Specifications

• Antigen: SEC62
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEC62
• Gene Alias: 3100002M17Rik; Ab2-292; AI844545; AW545092; Dtrp1; HTP1; hTP-1; membrane protein SEC62, S.cerevisiae, homolog of; Sec62; SEC62 homolog; SEC62 homolog (S. cerevisiae); SEC62 homolog, preprotein translocation factor; SEC62 preprotein translocation factor; Tloc1; TP-1; translocation protein 1; Translocation protein SEC62
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7095
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.07 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q99442
• Gene Symbols: SEC62
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Sec62. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG