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Secretogranin-5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980984
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50-198-0984 100 μL
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Catalog No. 50-198-0984 Supplier Bioss Supplier No. BS10762R
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Rabbit Polyclonal Antibody

Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Specifications

Antigen Secretogranin-5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Scg5
Gene Accession No. P05408
Gene Alias 7B2; AI325031; BOS_10512; C-terminal peptide; hypothetical protein MGC73132; LOC100341807; Neuroendocrine protein 7B2; neuronal endocrine protein; N-terminal peptide; P SGNE1; P7B2; Pituitary polypeptide; prohormone convertase chaperone; Scg5; Secretogranin V; secretogranin V (7B2 protein); Secretogranin-5; Secretory granule endocrine protein I; secretory granule neuroendocrine protein 1; secretory granule neuroendocrine protein 1, 7B2 protein; Secretory granule neuroendocrine, protein 1 (7B2 protein); secretory granule, neuroendocrine protein 1; secretory granule, neuroendocrine protein 1 (7B2 protein); SGNE1; Sgne-1; SgV; zgc:73132
Gene Symbols Scg5
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Secretogranin-5.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6447
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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