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Invitrogen™ Seipin Polyclonal Antibody
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Catalog No. PIPA559966
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100 μL
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PIPA559966 100 μL
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Catalog No. PIPA559966 Supplier Invitrogen™ Supplier No. PA559966
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Rabbit Polyclonal Antibody

Immunogen sequence: PTVSHLSPVH FYYRTDCDSS TTSLCSFPVA NVSLTKGGRD RVLMYGQPYR VTLELELPES PVNQDLGMFL VTISCYTR Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 51%.

This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Seipin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BSCL2
Gene Accession No. Q96G97
Gene Alias 2900097C17Rik; AI046355; Berardinelli-Seip congenital lipodystrophy 2 (seipin); Berardinelli-Seip congenital lipodystrophy 2 homolog (seipin); Bernardinelli-Seip congenital lipodystrophy 2 homolog; Bernardinelli-Seip congenital lipodystrophy type 2 protein; Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog; bscl2; bscl2 {ECO:0000250; BSCL2, seipin lipid droplet biogenesis associated; G protein gamma 3 linked; Gng3lg; HMN5; MNCb-2630; PELD; seipin; SPG17; UniProtKB:Q96G97}
Gene Symbols BSCL2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Seipin. Recombinant protein control fragment (Product #RP-90433).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26580
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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