Invitrogen™ Selenoprotein W Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567614

Catalog No. PIPA567614

Description

Selenoprotein W Polyclonal Antibody for IHC (P)

This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle, heart and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A retroprocessed pseudogene for this locus has been identified on chromosome 1.

Specifications

• Antigen: Selenoprotein W
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SELENOW
• Gene Alias: Selenoprotein W; selenoprotein W, 1; selenoprotein W, muscle 1; Selenow; SelW; Sepw1
• Host Species: Rabbit
• Purification Method: affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6415
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P63302
• Gene Symbols: SELENOW
• Immunogen: Synthesized peptide derived from human Selenoprotein W.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov