SELS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-0332	Proteintech Group Inc 155911AP150UL	150 μL

Description

The p70 S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70 kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70 S6 kinase is predomitly localized in the cytoplasm, and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response, and tissue repair. p70 S6 kinase acts downstream of phosphoinositide (PI) 3-kinase, and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70 S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70 S6 kinase and overexpression are seen in some breast cancer cell lines.

Specifications

• Antigen: SELS
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q8VHV8, Q9BCZ4, Q9BQE4
• Gene ID (Entrez): 109815, 286900, 55829
• Immunogen: SELS Fusion Protein Ag7928
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SELENOS

• Concentration: 0.14 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AD 015, ADO15, SBBI8, selenoprotein S, SELS, SEPS1, VIMP
• Gene Symbols: Selenos
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody