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Invitrogen™ SEMA3A Monoclonal Antibody (M317)
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Catalog No. PIMA547732
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100 μL
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PIMA547732 100 μL
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Catalog No. PIMA547732 Supplier Invitrogen™ Supplier No. MA547732
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Description

Mouse Monoclonal Antibody

The antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A and adult mouse brain lysates.

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA3A
Applications Western Blot
Classification Monoclonal
Clone M317
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene SEMA3A
Gene Accession No. O08665, Q14563, Q63548
Gene Alias COLL1; coll-1; collapsin 1; collapsin-1; HH16; Hsema-I; Hsema-III; MGC133243; sema D; sema domain, immunoglobulin domain (Ig), short basic domain, sec; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; sema III; SEMA1; SEMA3A; Semad; SEMAIII; SEMAL; Semaphorin 3a; semaphorin D; semaphorin III; semaphorin L; semaphorin-3A; Semaphorin-D; SemD
Gene Symbols SEMA3A
Host Species Mouse
Immunogen Clone M317 was generated from a synthetic peptide (coupled to carrier protein) corresponding to amino acids in the central region of human Sema3A. The sequence used is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10371, 20346, 29751
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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