Invitrogen™ SEMA3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118891

Catalog No. PIPA5118891

Description

Antibody detects endogenous levels of total SEMA3A.

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Specifications

• Antigen: SEMA3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEMA3A
• Gene Alias: COLL1; coll-1; collapsin 1; collapsin-1; HH16; Hsema-I; Hsema-III; MGC133243; sema D; sema domain, immunoglobulin domain (Ig), short basic domain, sec; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; sema III; SEMA1; SEMA3A; Semad; SEMAIII; SEMAL; Semaphorin 3a; semaphorin D; semaphorin III; semaphorin L; semaphorin-3A; Semaphorin-D; SemD
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10371, 20346, 29751
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O08665, Q14563, Q63548
• Gene Symbols: SEMA3A
• Immunogen: A synthesized peptide derived from human SEMA3A(Accession Q14563), corresponding to amino acid residues F706-G756.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov