Invitrogen™ SEMA3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595239

Catalog No. PIPA595239

Description

Human Semaphorin 3A shares 93% and 94% amino acid (aa) sequence identity with mouse and rat Semaphorin 3A, respectively. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: 293T whole cell, A549 whole cell, HELA whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Specifications

• Antigen: SEMA3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEMA3A
• Gene Alias: COLL1; coll-1; collapsin 1; collapsin-1; HH16; Hsema-I; Hsema-III; MGC133243; sema D; sema domain, immunoglobulin domain (Ig), short basic domain, sec; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; sema III; SEMA1; SEMA3A; Semad; SEMAIII; SEMAL; Semaphorin 3a; semaphorin D; semaphorin III; semaphorin L; semaphorin-3A; Semaphorin-D; SemD
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10371
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: Q14563
• Gene Symbols: SEMA3A
• Immunogen: E.coli-derived human Semaphorin 3A recombinant protein (Position: K550-V771).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG