Invitrogen™ SEMA3E Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578297

Catalog No. PIPA578297

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved approximately 400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.

Specifications

• Antigen: SEMA3E
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEMA3E
• Gene Alias: 6430702L12; AA408817; coll-5; KIAA0331; mKIAA0331; M-sema H; M-SEMAH; M-SemaK; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; sema H; Sema3e; SEMAH; semaphorin 3E; semaphorin-3E; Semaphorin-H; Semh
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9723
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA
• Concentration: 0.58 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O15041
• Gene Symbols: SEMA3E
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Semaphorin 3E. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG