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Invitrogen™ SEMA4G Polyclonal Antibody
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Catalog No. PIPA558357
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100 μL
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PIPA558357 100 μL
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Catalog No. PIPA558357 Supplier Invitrogen™ Supplier No. PA558357
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ATPRMTIPYE ELSGTRHFKG QAQNYSTLLL EEASARLLVG ARGALFSLSA NDIGDGAHKE IHWEASPEMQ SKCH Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 92%.

The SEMA4G gene encodes semaphorin 4G, a member of the semaphorin protein family known for their roles in cellular guidance, signaling, and development. Semaphorin 4G is involved in axonal guidance, where it influences the direction and growth of neurons by interacting with receptor complexes such as plexins. This interaction is critical in neural development, contributing to the proper formation of neural circuits by ensuring that neurons connect accurately and functionally. Beyond its role in the nervous system, SEMA4G also participates in immune responses, where it modulates the activity and migration of immune cells, influencing processes like inflammation and immune surveillance. This protein's modulation of cell-to-cell communication and migration extends to its implications in cancer, where altered semaphorin signaling can impact tumor progression and metastasis through changes in cell adhesion and migration properties. Research into SEMA4G continues to investigate its precise mechanisms and interactions, providing insights into therapeutic opportunities in neural disorders and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA4G
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SEMA4G
Gene Accession No. Q9NTN9
Gene Alias AI507908; AW554132; KIAA1619; KIAA1619FLJ20590; MGC102867; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; Sema4g; semaphorin 4G; semaphorin-4G
Gene Symbols SEMA4G
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SEMA4G. Recombinant protein control fragment (Product #RP-95590).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57715
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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