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Invitrogen™ SEMA6D Polyclonal Antibody
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Catalog No. PIPA543381
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100 μL
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PIPA543381 100 μL
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Catalog No. PIPA543381 Supplier Invitrogen™ Supplier No. PA543381
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Description

Rabbit Polyclonal Antibody

Peptide sequence: VSFPEDDEPL NTVDYHYSRQ YPVFRGRPSG NESQHRLDFQ LMLKIRDTLY Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA6D
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SEMA6D
Gene Accession No. Q8NFY4
Gene Alias 1110067B02Rik; AA409156; D330011G23; FLJ11598; hypothetical protein LOC406272; KIAA1479; KIAA1479FLJ11598; mKIAA1479; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Sema6d; sema6d protein; semaphorin 6D; semaphorin-6D; wu:fi06a12; wu:fi76a10; zgc:56170
Gene Symbols SEMA6D
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human SEMA6D (aa 21-70).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80031
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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