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SEMA6D Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985033
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50-198-5033 100 μL
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Catalog No. 50-198-5033 Supplier Bioss Supplier No. BS2943R
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Description

Rabbit Polyclonal Antibody

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Specifications

Antigen SEMA6D
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SEMA6D
Gene Accession No. Q8NFY4
Gene Alias 1110067B02Rik; AA409156; BOS_10967; D330011G23; FLJ11598; hypothetical protein LOC406272; Kiaa1479; KIAA1479FLJ11598; mKIAA1479; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Sema6d; sema6d protein; semaphorin 6D; semaphorin-6C; Semaphorin-6D; wu:fi06a12; wu:fi76a10; zgc:56170
Gene Symbols SEMA6D
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SEMA6D.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80031
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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